水車攪拌式の細胞にやさしいバイオリアクター

論文例

iPS細胞

Characterization of the Aeration and Hydrodynamics in Vertical-Wheel Bioreactors - 2022 Neto et al. 

Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufactruing of Allogeneic Pluripotent Stem Cell Products - 2022 Lee et al.

Transcriptome Profiling of Human Pluripotent Stem Cell‐Derived Cerebellar Organoids Reveals Faster Commitment Under Dynamic Conditions - 2021 Silva et al.

Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High-Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors - 2021 Borys et al.

Computational Fluid Dynamic Characterization of Vertical-Wheel Bioreactors Used for Effective Scale-up of Human Induced Pluripotent Stem Cell Aggregate Culturess - 2021 Dang et al.

Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining - 2020 Silva et al.

Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products - 2020 Lee et al.

Optimized Serial Expansion of Human Induced Pluripotent Stem Cells Using Low-Density Inoculation to Generate Clinically Relevant Quantities in Vertical-Wheel Bioreactors - 2020 Borys et al.

Strategies for the Expansion of hiPSCs as Aggregates in Single-Use Vertical-Wheel Bioreactors - 2019 Nogueria et al.

Scalable Culture of Human Induced Pluripotent Cells on Microcarriers Under Xeno-Free conditions Using Single-Use Vertical-Wheel Bioreactors - 2018 Rodrigues et al.

Scalable Culture Of Human Induced Pluripotent Stem Cells On Microcarriers Under Xeno-Free Conditions - 2018 Rodrigues et al.

間葉系幹細胞

Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufactruing of Allogeneic Pluripotent Stem Cell Products - 2022 Lee et al.

Bioreactor Parameters for Microcarrier-Based Human MSC Expansion Under Xeno-Free Conditions in a Vertical-Wheel System - 2020 Lembong et al.

Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products - 2020 Lee et al.

Quality Manufacturing of Mesenchymal Stem/Stromal Cells Using Scalable and Controllable Bioreactor Platforms - 2018 Jung et al.

その他

Initial Power Measurements for a Family of Novel Vertical-Wheel Bioreactors - 2022 Croughan et al.

記事

Defined Biomatrices Accelerate MSC Manufacturing Across Scales - White Paper