細胞製剤のスケールアップ培養に最適

論文例

iPS細胞

Suspension Culture on Microcarriers and as Aggregates Enables Expansion and Differentiation of Pluripotent Stem Cells - 2023 Vallabhaneni et al.

Suspension Culture Improves iPSC Expansion and Pluripotency Phenotype - 2023 Cuesta-Gomez et al.

Characterization of the Aeration and Hydrodynamics in Vertical-Wheel Bioreactors - 2022 Neto et al. 

Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufactruing of Allogeneic Pluripotent Stem Cell Products - 2022 Lee et al.

Transcriptome Profiling of Human Pluripotent Stem Cell‐Derived Cerebellar Organoids Reveals Faster Commitment Under Dynamic Conditions - 2021 Silva et al.

Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High-Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors - 2021 Borys et al.

Computational Fluid Dynamic Characterization of Vertical-Wheel Bioreactors Used for Effective Scale-up of Human Induced Pluripotent Stem Cell Aggregate Culturess - 2021 Dang et al.

Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining - 2020 Silva et al.

Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products - 2020 Lee et al.

Optimized Serial Expansion of Human Induced Pluripotent Stem Cells Using Low-Density Inoculation to Generate Clinically Relevant Quantities in Vertical-Wheel Bioreactors - 2020 Borys et al.

Strategies for the Expansion of hiPSCs as Aggregates in Single-Use Vertical-Wheel Bioreactors - 2019 Nogueria et al.

Scalable Culture of Human Induced Pluripotent Cells on Microcarriers Under Xeno-Free conditions Using Single-Use Vertical-Wheel Bioreactors - 2018 Rodrigues et al.

Scalable Culture Of Human Induced Pluripotent Stem Cells On Microcarriers Under Xeno-Free Conditions - 2018 Rodrigues et al.

間葉系幹細胞

Upscaling Human Mesenchymal Stromal Cell Production in a Novel Vertical-Wheel Bioreactor Enhances Extracellular Vesicle Secretion and Cargo Profile - 2024 Jeske et al.

Computer Controlled Expansion of Equine Cord Blood MSCs on Microcarriers in 3L Vertical-Wheel Bioreactors - 2023 Roberts et al.

Bioprocess Development for Cord Blood Mesenchymal Stromal Cells on Microcarriers in Vertical‐Wheel Bioreactors - 2023 Roberts et al.

Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufactruing of Allogeneic Pluripotent Stem Cell Products - 2022 Lee et al.

Bioreactor Parameters for Microcarrier-Based Human MSC Expansion Under Xeno-Free Conditions in a Vertical-Wheel System - 2020 Lembong et al.

Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products - 2020 Lee et al.

Quality Manufacturing of Mesenchymal Stem/Stromal Cells Using Scalable and Controllable Bioreactor Platforms - 2018 Jung et al.

胚性幹細胞

Metabolic Switching, Growth Kinetics and Cell Yields in the Scalable Manufacture of Stem Cell‑Derived Insulin‑Producing Cells - 2024 Iworma et al.

Suspension Culture on Microcarriers and as Aggregates Enables Expansion and Differentiation of Pluripotent Stem Cells - 2023 Vallabhaneni et al.

免疫細胞

Combined Role of Interleukin-15 Stimulated Natural Killer Cell-Derived Extracellular Vesicles and Carboplatin in Osimertinib-Resistant H1975 Lung Cancer Cells with EGFR Mutations - 2024 Aakash et al.

その他

Initial Power Measurements for a Family of Novel Vertical-Wheel Bioreactors - 2022 Croughan et al.

記事

Defined Biomatrices Accelerate MSC Manufacturing Across Scales - White Paper